Getting Healthier Now

A Blog About Digestive Health

Tag: vagal nerve

Probiotics: Larger Doses Making a Big Difference

Lactoferrin for SIBO? It seems to be helping most by lowering my inflammation, and I’ll continue taking it daily, but I’ve noticed it also tends to constipate me, which is a bit of a paradox because while the lactoferrin should help kill pathogens and destroy biofilm, a constipated gut is at continued risk for SIBO.

In an effort to counteract this, and get my gut moving, I’ve gone back to the most basic approach of all: probiotics, and lots of them. I figure I can combine this with the lactoferrin, taking the two of them offset as many hours as possible. Lactoferrin with food, and probiotics between meals.

Why not more of my kefir and sauerkraut? I’ve found “enough” is helpful, but too much of either can make me back slide, and I’m not sure why. Especially when my GI tract is sluggish, I think kefir may worsen SIBO by building more biofilm. If anyone has ever tried cleaning a used kefir mason jar, with its thick accumulation of flora after just a few batches, you know what I’m talking about.

If I could deposit the healthy kefir biofilms exclusively in my colon, that would be another matter, but I’ve tried this, more than a few times. Unfortunately, retention enemas with kefir have given me relief only in acute situations, and longer term use doesn’t seem to address all my symptoms.

Probiotics, on the other hand, generally don’t have a reputation for colonizing our guts. Many see this as a drawback, but in the case of SIBO, I am hoping it’s an advantage. Perhaps these temporary upper gut residents will outcompete small intestinal pathogens without setting up shop and compounding the problem.

Recently I came across an interesting evaluation of some common probiotics on PubMed’s site. Note the section on VSL#3, which is a mixture of gram positive bacteria (which do not contain highly inflammatory lipopolysaccharide). Like many probiotics, VSL#3 is a mixture of flora originally harvested from a healthy human donor.

Take note of what it says about VSL#3 helping to heal the gut barrier function. “Leaky gut” is another term for this, and I’ve no doubt that’s one of my biggest problems.

Barrier function was also assessed using mannitol flux assays and after 4 weeks of VSL#3 treatment, barrier function normalized in these mice. Using the T84 human intestinal epithelial cell line it was further shown that VSL#3 and products secreted by these bacteria enhanced intestinal epithelial barrier function in vitro, and pre-exposure of T84 monolayers to VSL#3 provided a dose-dependent decrease in cellular invasion by the pathogenic bacteria Salmonella enterica serovar Dublin. A subsequent study corroborated these findings and further found that VSL#3 upregulated the expression of several mucins which are postulated to play an important cytoprotective role in host defense against pathogens [21].

The expense is a factor, and the primary reason I’ve never stuck with VSL#3 for very long, but could it be a “poor man’s fecal transplant”? With FMT being very costly in a clinic setting, and since I don’t currently have access to a donor for DIY at home, I’m going to give this a shot. The only difference being I’ll take this probiotic orally in addition to retention enemas.

Speaking of upper gut colonization, would the fact that VSL#3 is human-sourced mean its flora will attach permanently to the wall of the small intestine? Likely, the answer is no. This has something to do with how probiotics are manufactured. For some reason, the adherence of probiotic strains on the gut wall is usually not that good, no matter how the flora was originally harvested.

I began with a retention enema using 8 pills of VSL#3 in about 4 ounces of distilled water, using an empty and rinsed Fleet enema bottle. About 5 minutes later I felt my long-gone sense of smell returning. I noticed a basket of essential oils that had been on my dresser for months. Hard to imagine my nose had been so impaired this wasn’t fragrant to me until now, but that’s indeed the case.

About 20 minutes later, I noticed my tinnitus getting quieter, and my whole body relaxing. My mood improved. Joint pain was lessened, also.

Oral administration of VSL#3 was my next step. I took 8 capsules, 2 doses of 4 each, that first day.

I’ve been taking 4 capsules, 3 times per day, between meals, ever since, and drinking 2 pints of distilled water with each dose. I add trace minerals to my water. I only did the retention enema on day 1, and am hoping I can stop it altogether or reduce to once per week.

Now, three days in to the 12 capsules per day oral protocol, here’s a an intriguing list of symptoms where I’m definitely seeing improvements. It’s worth noting a great many of these issues came about after taking fluoroquinolone antibiotics. How much of being “floxed” is due to altered flora?

I should underscore that probiotics are nothing new for me, and VSL#3 is one I’ve used in the past to stop ulcerative colitis flares, but I’ve never taken it in this quantity, nor have I done it with the same frequency, plus I’m also combining the doses with enough water that my stomach acid is probably being diluted, which means more flora survives to reach the colon.

I also think, subjectively, my symptoms were never this bad in previous years, so I never had this far to “bounce back”.

So many symptoms are linked. Overall, I sense a restoration of my vagal nerve function. Huge relief from a constant stuffy nose (neurological, not from typical blockage), my pulse and BP are nice and low, and my sleep patterns and mood are evening out. No more blazing hot colon, lower back and neck, either.

The one thing that hasn’t changed yet, and this is fairly upsetting, is fatigue.

At first I felt strength returning to my legs, and I’d hoped this effect would snowball, but it’s less noticeable now than it was when I first started. Maybe I need to maintain the retention enemas. Another possible explanation for this is lipopolysaccharide being released, as gram positive flora is duking it out with the gram negative ones. If it’s happening in my small intestine, this means more LPS in the bloodstream. Perhaps sorting it all out is just a function of time.

Fatigue is the core of my illness, and Cipro and Levaquin were the triggers for it. I hope as I continue my therapy this will resolve, and it’s clear 3 days of anything gut-related is not enough time to know the longer term potential for healing.

I do hold out lots of hope I can eventually get my energy back, given all the other smaller improvements I’ve seen in the early going. I actually had my housemate take a “before” picture last night, because I’m so shrunken from the SIBO: 6 feet tall and 145 lbs. Underweight is nothing to mess around with, and I know it can significantly impair immunity. I had to do something, and i think i’m finally on the right track.

Have you tried a similar approach, taking large, longer term doses of probiotics? Which type works best for you? And if anyone has figured out a way to “brew” them to reduce the cost, let us know in the comments section below. Thanks.

 

Comments

Watch Movie Online Ghost in the Shell (2017) subtitle english

Poster Movie Ghost in the Shell 2017

Ghost in the Shell (2017) HD

Director : Rupert Sanders.
Writer : Masamune Shirow.
Producer : Ari Arad, Avi Arad, Maguy R. Cohen, Steven Paul.
Release : March 29, 2017
Country : United States of America.
Production Company : Paramount Pictures, DreamWorks SKG, Grosvenor Park Productions.
Language : English.
Runtime : 100 min.
Genre : Action, Drama, Science Fiction.

‘Ghost in the Shell’ is a movie genre Action, was released in March 29, 2017. Rupert Sanders was directed this movie and starring by Scarlett Johansson. This movie tell story about Based on the internationally-acclaimed sci-fi property, GHOST IN THE SHELL follows the Major, a special ops, one-of-a-kind human-cyborg hybrid, who leads the elite task force Section 9. Devoted to stopping the most dangerous criminals and extremists, Section 9 is faced with an enemy whose singular goal is to wipe out Hanka Robotic’s advancements in cyber technology.

Do not miss to Watch movie Ghost in the Shell (2017) Online for free with your family. only 2 step you can Watch or download this movie with high quality video. Come and join us! because very much movie can you watch free streaming.

Watch movie online Ghost in the Shell (2017)
Incoming search term :

Ghost in the Shell 2017 HD English Full Episodes Download
Ghost in the Shell 2017 Episodes Online
streaming movie Ghost in the Shell
Ghost in the Shell 2017 Online Free Megashare
Ghost in the Shell 2017 English Full Episodes Free Download
Ghost in the Shell 2017 English Full Episodes Watch Online
Ghost in the Shell 2017 English Full Episodes Download
watch full film Ghost in the Shell 2017
Ghost in the Shell 2017 Episodes Watch Online
Ghost in the Shell movie streaming
Watch Ghost in the Shell 2017 Online Free
Ghost in the Shell 2017 English Episodes
Watch Ghost in the Shell 2017 Online Free Putlocker
download Ghost in the Shell movie
watch Ghost in the Shell 2017 film now
Watch Ghost in the Shell 2017 Online Free Viooz
Watch Ghost in the Shell 2017 Online Putlocker
Ghost in the Shell 2017 Watch Online
Ghost in the Shell 2017 English Episodes Free Watch Online
live streaming movie Ghost in the Shell
Ghost in the Shell 2017 HD Full Episodes Online
film Ghost in the Shell 2017 trailer
Ghost in the Shell 2017 Full Episodes Online
Ghost in the Shell streaming
Watch Ghost in the Shell 2017 Online Viooz
Ghost in the Shell 2017 Full Episodes Watch Online
watch full Ghost in the Shell 2017 film
Watch Ghost in the Shell 2017 Online Free megashare
download movie Ghost in the Shell 2017 now
Watch Ghost in the Shell 2017 Online Megashare
watch Ghost in the Shell 2017 movie online now
Ghost in the Shell 2017 For Free Online
Ghost in the Shell 2017 movie download
Ghost in the Shell 2017 English Episode
trailer film Ghost in the Shell
Ghost in the Shell 2017 Full Episode
Watch Ghost in the Shell 2017 Online Free putlocker
Ghost in the Shell 2017 English Full Episodes Online Free Download
film Ghost in the Shell
live streaming movie Ghost in the Shell online
Ghost in the Shell 2017 For Free online

Lufenuron: Healing Chronic Fatigue & More

A month or so ago I was feeling “okay” but not great. Ever since I was given Levaquin antibiotics in the ER for food poisoning, about 4 years ago, I’ve had CFS/ME, brain fog, tinnitus, , , food intolerance, asthma, , sinus and skin issues, depression/anxiety, rising blood sugar and constipation.

Does this sound familiar to any of you? What’s the common thread?

I’ve had fungal overgrowth, inside and out, for years, made much worse by broad spectrum antibiotics. Doctors shuffle me out of their offices when I ask for Nystatin powder, or other prescription antifungals, despite having obvious plaques on my scalp, feet, face, chest and groin, plus sinus and lung irritations consistent with candidiasis.

I have tried my best to control it with diet and herbals, like , , and . It’s a chronic infection, so I’m slowly feeling worse and worse. Recently, even downing healthy amounts of cultured veggies and homemade kefir (both are powerful probiotics) hasn’t been very effective.

Flash back to a month ago, . I had GERD, muscle spasms, insomnia, asthma. In the days that followed, I knew I needed to do something more drastic to get the upper hand. was helpful, but not something I wanted to take longer term. I heard about in an online forum. Not for human use, this chitin-inhibitor dissolves flea eggs, and… the outer shell of candida. Mammals don’t have chitin, so it’s apparently safe for dogs, cats .

It’s typically given for the first week of every month, daily, with a high fat meal (so it will deposit in tissues and be slow-released, rather than quickly leaving via the GI tract), then for the remaining 3 weeks of each month it goes to work destroying fungal overgrowth.

Yes, humans aren’t supposed to use it, but there’s nothing stopping anyone from treating their gorilla, so that’s what I set out to do. Curiously, ever since i gave my pet ape pure Lufenuron, we both started to feel much better.

This is my record of that adventure, which periodically:

Day 1: dosage was 2 grams, and by the middle of Day 2, a major burst of mental clarity occurred. By that evening, the ability to sleep deeply had returned, to the point of waking on Day 3 — after 10 hours with no dreams, out like a light — and muscles felt much less sore, plus joint pain had disappeared.

To reiterate: during a 7 day total treatment “loading” window, 2 grams were administered daily, with a high-fat meal.

By Days 4 and 5, die-off symptoms emerged, which is not surprising, and lasted until Day 12: diarrhea, blurred vision, fatigue, insomnia and body aches. The good news: no more constipation, but it took 10 days for die-off to subside, and detoxing continues.

Day 13: colon inflammation is gone, and a healthy, sometimes ravenous appetite has emerged. I’m finding I don’t have to as much to relieve . I also think my tinnitus is a little better. It comes and goes, but I have more moments of silence.

Today, Day 14, upon waking, the gorilla is quite spunky, feeling like a randy teenager (Lufenuron might replace Viagra), and in the afternoon, muscles unwind in a characteristic activation of the parasympathetic nervous system, as nap time beckons. cheap phentermine The vagal nerve is working now, which is intriguing! Was candida ? It’s amazing how long, hot showers are enjoyable again (for my monkey). Relaxation is happening; anxiety is disappearing. There’s no more being stuck in fight-or-flight mode.

Healing like this is emotional, .

By the way, people should not treat their primate’s flea problem with pure Lufenuron unless they’ve consulted a veterinarian, and should never treat themselves using medication not approved for humans. In fact, any and all new treatments contemplated should first be discussed with a physician. Please .

With that said, CFS symptoms are improving, POTS also, along with so much more. Go, monkey, go.

To be .

UPDATE: I tried Lufenuron three times, and while the first dose provided incredible relief, when I took it again one month later it was only half as effective as it had initially been, and by the third dose, another month after that, it barely had an impact on my fungal overgrowth at all. This was despite mixing it with herbals.

Luckily I learned something valuable from the experiment: it seemed my immune system was the problem, so I began looking for something that could boost my body’s innate ability to fight candida. That led me to iodine, and a potential connection between fluorquinolone antibiotics, like Cipro and Levaquin, and hypothyroidism. . . So far the results have been really encouraging, and unlike Lufenuron, iodine is both inexpensive and subject to much greater testing in humans.

If you enjoy this blog, you can support my work by , or by purchasing any product linked in articles. It costs you nothing extra, and helps me continue writing. Thanks!

IBD and Vagus Nerve Issues: the Gut/Neck Axis?

Is it possible some of us with IBD also have an underlying neck injury, which drives gut inflammation?

The average human’s head is about the weight of a bowling ball, so it’s not surprising the neck can experience trauma due to an acute injury, or chronic misalignment through smart phone use (text-neck!) , poor posture on the job, inactivity, etc.

For me, inflammatory conditions began with antibiotic use, but they got MUCH WORSE after a neck injury, sustained in a traffic accident, several years ago. Initial symptoms were a stuffy, blocked nose without congestion, then asthma, GERD, sinusitis, tinnitus, TMJ, constipation, IBS, and a few years later ulcerative colitis.

UC lead to inactivity, more time spent in front of a computer, degenerative changes in my neck, throw in a dose of Levaquin for food poisoning, then SIBO, food intolerances, hyperadrenergic POTS, heart palpitations, even worse GERD, panic attacks/anxiety, and finally fibromyalgia-like pain and chronic fatigue.

I’ve had quite a few breakthroughs with health in the last few years, but the most profound occurred about a week ago when I realized many of these symptoms I’ve had for years (while directly linked to antibiotics use) are also mediated by my posture, specifically, if my neck is in an unhealthy kyphotic curvature (the reverse of a normal alignment, called lordosis) .

What’s the inflammation connection? The vagus (also called ‘vagal’) nerve runs throughout the body, getting its name “the wanderer” from the widespread path it travels, but it threads its way through a narrow channel in the cervical spine, such that compression of soft tissues between the upper cervical vertebrae can impair a lot of vagal function. This is my layperson’s view. Let’s see if our experience bears this out.

Given that the “fight or flight” response includes a clenching of neck muscles, in preparation for fleeing, is it possible this reduction of parasympathetic response (relaxation) is partially a built-in biomechanical feature of our bodies? If so, chronic stress, with its attendant tightening of that upper cervical spine, may be a vicious cycle — one that we can fairly easily monitor and turn around!

In a previous post I mentioned the posture pump I’ve been using. It’s fairly inexpensive, and definitely effective, but also impractical for anyone out and about in the world. For a cheaper, more portable option, try a NeckBone Pillow.

But what if we could do something similar with no equipment at all? Enter the “Alexander Technique“.

I’m warning you: this practice is so simple, you may wonder if you’re doing much at all, but when performed properly, you’ll notice a big difference. For some, this perfecting of posture and movement may be all you’ll need.

I have developed the habit, in just a few short days, of “sitting tall” in my car, as I’m driving. I tilt my head back ever so slightly, so that my chin is jutting forward. Lordosis! I can feel my nasal passages opening, my sinuses draining. I also notice my blood pressure dropping, as pressure (I assume) is taken off my vagus nerve.

Furthermore, when I adopt this posture throughout the day, I notice the “heat” that fills my entire lower abdomen, and gives rise to gut inflammation, mucus in stools, dull pain — this totally goes away. Hmmm…

I know I’m not the only person who experienced the sudden onset of hyperadrenergic POTS after a neck injury. A cardiologist I consulted a few years ago about my POTS symptoms mentioned one hyperadrenergic patient of his who was a perfectly healthy woman until she got whiplash in a car crash. I’m in touch with someone else on Facebook who had a skiing accident. She hurt her upper cervical spine, and has had POTS (the low blood pressure type) ever since.

This is certainly sad, especially given how little the allopathic doctors understand about hyperadrenergic POTS, UC or other forms of IBD — typically they are good at treating acute symptoms — but if permanent neck trauma is indeed part of a range of inflammatory triggers, we can at least try to heal vagal nerve function from the gut side of the equation.

Our enteric nervous system is a feedback loop, so the Gut/Brain/(Neck?) Axis works in reverse, and if we have mechanical impairment “upstairs”, boosting gut flora signaling via the vagal nerve, from gut to brain, may compensate for the neurological impairment in some people. I’ve been tinkering a lot with gut flora (in yogurt, sauerkraut, my own homemade kefir and probiotics) that may promote parasympathetic (relax and digest) activity. More on that in a future post.

Does anyone else have a history of neck injury or strain that could explain more global issues? If so, I’d appreciate hearing from you in the comments section.

EDIT: since writing this article not long ago, I’ve spoken to huge numbers of IBD sufferers who had a neck injury immediately preceding the onset of their illness. I’d appreciate your feedback. If you’ve had a similar experience and would like me to include your story in a future post, send me an email via the contact form. Thanks!