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Tag: helminthic therapy (page 1 of 3)

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Uh-oh… Copper Deficiency Mimics Low B-12

It’s been quite a health adventure the last year or more, and you can read a quick update here. I had thought correcting a B-12 deficiency was all I needed to reclaim my health, but things got a bit more complicated.

It turns out copper deficiency can mimic low B-12, with many of the same symptoms of neurodegeneration, fatigue, skin inflammation and joint pain, due to disruption of collagen. I’ve been losing bone mass and developing arthritis – these are also signs of low copper. Here’s a full list of symptoms I’ve had during the last year.

The prevailing naturopathic attitude is we’re all copper toxic, so few of us would believe we could be deficient. Compounding the likelihood in an otherwise healthy population are corporate farming practices. Copper-rich foods simply can’t be grown in depleted soil. And sadly, few doctors ever think of copper deficiency when doing differential diagnosis. I’ve never once had copper levels tested by a physician, despite years of GI problems.

What’s most unsettling – unlike B-12 where there’s a fair amount of lag-time between low serum levels and permanent harm – copper deficiency neurodegeneration often cannot be reversed with supplementation. What does get repaired, eventually, may take months – or even years – of repletion. You can imagine my shock after reading this.

wake-up

Next, I looked up dietary sources of copper. Due to my food intolerances I wasn’t eating any copper-rich foods. Couple this with years of gut inflammation, malabsorption, and regardless of any testing I might do with my doctor, it was clear I needed to supplement with a modest 2 mg of copper soon, just based on my symptoms and diet.

The proper way to take it is in combination with zinc. Too much zinc will deplete copper, so a proper balance is important. Also worth noting is colloidal silver, if taken orally or by IV, can deplete copper, sometimes with dramatic results. This may have happened with me a few years ago after taking colloidal silver for SIBO.

The good news is a few short days after I started taking 2 mg copper my eyesight was much sharper, mood and cognition improved a bit, and I got a noticeable reduction in fatigue. A week later I increased my dose to 4 mg, plus 30 mg zinc, and noticed less joint pain and stiffness. Shortly thereafter, my skin began feeling less fragile. Perhaps my collagen synthesis has been improving, and I may be correcting an anemia due to this deficiency.

Copper is also essential to keep blood vessels and arteries flexible and strong, which could explain my increased vericose veins and petechiae in the last year. It’s thought most cases of aortic rupture are preventable if people get adequate copper in food.

My face has had a red glow for the last couple of years, in recent months my chest and abdomen, and sometimes even my whole body has, too. This flushing could be due to histamine intolerance, and it’s important to note copper (along with B-6 and vitamin C) is required to create DAO enzyme to break down histamine. Sure enough, one thing I noticed after a few weeks supplementation is I’m no longer flushed from head to toe most of the day. Perhaps eventually I’ll be able to tolerate some higher histamine foods.

Given the risk of nervous system damage from long term deficiency, I decided not to wait for testing before supplementing with safe amounts. My plan is to stay at 4 mg copper daily with 30 mg zinc (which is what healthy people get in a copper-rich diet) until I can schedule hair analysis and serum tests to determine the correct protocol for repletion.

Where I’m still hoping to see improvement is more subtle, which appears to be low dopamine. Given its effect on brain health, copper is required to generate important neurotransmitters. Among other things, low dopamine (key to reward and accomplishment) was probably making it tough to update this blog for the last 16 months. With that said, onward and upward.

How many of us diagnosed and treated for B-12 deficiency are also copper deficient? If any of this sounds familiar, please join us in the comments section, and share your own story.

A Long-overdue GHN Update

Since my last post here, many months ago, I got short term improvement from B-12 shots, but my serum levels were sky high and my doctor suggested I stop the injections. After an initial bounce I crashed, and began to have widespread inflammatory and neuroinflammatory issues. He theorized this may have been triggered by saturation with B-12. My serum B-6 was also quite high, despite never supplementing it.

A methylmalonic acid test was elevated, so after being off it for a few months, I continued to take 2,500 mcg oral B-12 and requested referral to a specialist who could check for genetic issues with methylation, but as my neck and back became more inflamed, and cognitive problems worsened, I was instead sent to a neurologist, who did a full workup: brain MRI, a soft-tissue MRA, hearing tests due to increasing tinnitus, a carotid artery test, and an EEG.

Other than a few white matter brain lesions (no change since a 2008 MRI) which may be congenital, these new tests were inconclusive. While I do have some degenerative changes to my cervical spine, autonomic dysfunction was the neurologist’s primary diagnosis. At this point, my symptoms were growing – you can read a list of them here.

A few weeks later, I saw a neurosurgeon and explained how pressing in various places on my neck, the base of my skull, and near the mastoid process behind my right ear, could often improve my autonomic issues. He pointed out a Chiari Malformation on my brain MRI but said “we don’t operate to fix dysautonomia”, which was yet another blind alley. I’ve yet to see an autonomic specialist for non-surgical treatment of this.

Flushing, at first just a red glow on my face, then eventually from near head to toe, has also been happening for about 14 months. My doctor tested for Carcinoid, and so far results don’t indicate it, which is a relief. Instead this may be related to a  mast cell disorder. I’ve learned certain kinds of flushing, even the rosacea which I have, can be caused by neurological problems.

What’s the root cause? It’s likely multifactoral, but nerve damage from repeated doses of fluoroquinolone antibiotics over the years, like Cipro and Levaquin, likely plays a huge role.  It was after a final dose of Levaquin in 2008 that I developed symptoms of hyperadrenergic POTS – primarily a vagus nerve malfunction – which triggers heat intolerance, trouble handling physical and emotional stress, and orthostatic intolerance.

However, these antibiotics did more than nerve damage, they wrecked my gut flora, and POTS is now thought to be autoimmune.

The best I’ve felt in recent years was while I hosted hookworm (small therapeutic doses) and did fecal transplants. Both of these protocols may boost vagus nerve tone, by lowering inflammation in the gut and boosting signaling from the enteric nervous system back to the brain, the “rest and digest” parasympathetic, which works opposite of “fight or flight” sympathetic.

My doctor suggested I try probiotics and hookworm again because he noted they seemed to help me, so I’ve been taking VSL#3 daily, plus Miyarisan tablets, which contain c. butyricum, and 15 weeks ago I did a dose of 50 necator americanus. While the initial side effects of helminthic therapy were rough, with spikes noted in blood work for eosinophils, I’m now feeling more benefits than allergic response, including no more asthma, healthier sinuses, and a big improvement of ulcerative colitis.

Concurrent with this, I remembered how good I felt one Summer when sunbathing for 15 minutes a day. I’ve had chronically low vitamin D and low testosterone. Sun exposure boosts both. I started laying out at noon each day a few months ago and it has been a great mood lifter. I also find I have better sleep quality when I get my daily 15 minutes. To discuss light therapy, its effect on mood, hormonal production and balancing sleep/wake cycles, join us here on Facebook.

I wanted to cover all the bases, and since sinusitis has been an ongoing problem for me, too, with green mucus indicative of staph colonization, I’ve begun daily rinses, which you can read about here. Two weeks later the mucus is thinning and has no color. I credit both the hookworm treatment and rinses to this recovery. Reducing sinus inflammation has improved anxiety, and my sleep is deeper. There’s a theory sinus inflammation from gram negative sinus flora can generate lipopolysaccharide (a potent inflammatory molecule) which in turn triggers brain inflammation.

Waking in the night gasping for air has been a problem during these last few months, and while I was scheduled for a sleep study I noticed a sudden improvement after a few days of sunbathing. There’s a vitamin D and sleep apnea correlation, mainly with regard to metabolic activity, so it’s possible Sun is good medicine for it. While I still have some brain fog, my mind feels sharper while sunbathing and I’m no longer waking at night. Since obstruction of upper airways can also contribute to apnea, sinus rinses are likely helping, too.

I’ve also been to see an oral surgeon after my dentist thought I could have dental infections contributing to fatigue and cognitive problems, but an oral surgeon did a panoramic x ray and said it looked fine. He noted sinus inflammation and recommended I keep doing my daily rinses.

I feel fortunate testing was able to rule out a lot, but if you see a pattern here, it’s that each protocol has helped a little – yet nothing has totally solved – what first appeared to be symptoms of low B-12. Now, just in the last month, I’m pretty sure I’ve figured out a key factor, and it may be a different deficiency, with very similar presentation.

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Movie ‘Un Profil pour deux’ was released in April 12, 2017 in genre Romance. Stéphane Robelin was directed this movie and starring by Pierre Richard. This movie tell story about Pierre, widowed and retired, has not been out of his house for two years. He discovers the joys of the internet thanks to Alex, a young man hired by his daughter to teach him the basics of computer science. On a meeting place, a charming young woman, Flora63, seduced by the romanticism of Pierre, offers her a first date. Lovers, Pierre is back. But on his profile he put a picture of Alex and not his own. Pierre must convince the young man to meet Flora in his place

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Movie ‘La La Land’ was released in September 12, 2016 in genre Comedy. Damien Chazelle was directed this movie and starring by Ryan Gosling. This movie tell story about Mia, an aspiring actress, serves lattes to movie stars in between auditions and Sebastian, a jazz musician, scrapes by playing cocktail party gigs in dingy bars, but as success mounts they are faced with decisions that begin to fray the fragile fabric of their love affair, and the dreams they worked so hard to maintain in each other threaten to rip them apart.

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Hookworm for Healing Prostatitis?

So seven weeks ago I did a 50 hookworm top-off dose, and I’m absolutely 100% allergy free right now: no asthma, no sneezing, and I’m also experiencing the characteristic lack of aches and pains I tend to enjoy when my hookworm are active and providing their benefits. This is now my third year of helminthic therapy, so my body is quite accustomed to it.

Side effects? Hardly any. A few weeks ago i had slightly increased mucus production in my nasal passages and sinuses, which is actually a sign of health for me, as this all disappeared when I got “floxed” with Levaquin antibiotics a few years ago. At that point my immune system was stunned. My nose always felt irritated, with a “tight” and “dry” sensation. Happily, I now have a very normal, unremarkable nose, and this means no more sinus headaches, either!

As far as gut function, I have a history of ulcerative colitis, and other than a brief flare that came on before my last dose of hookworm, I’ve been in total remission, for months. I was able to get rid of the flare using sodium butyrate enemas, and now it seems like my worms have it all under control.

Now, for something very interesting, indeed. In years past I’ve always noticed prostatitis is a problem for me as seasons change, particularly from Summer into Fall. Not so, this year, and perhaps this is also due to my hookworm! Why? My theory is prostatitis can be the result of seasonal allergies. In quite a few forums around the web I’ve noticed men wondering about a connection, and my experience could help to confirm it. I do hope in time hookworm will be put to use for this “off-label” condition, as I find it to be more beneficial than any other therapy I’ve tried!

It’s easiest for me to look at the prostatitis/allergy connection in terms of an inflammatory threshold. In past years, even when I was much younger, anything could be a potential trigger — too much coffee, alcohol, or spicy food, too much sitting, not enough exercise, infrequent sexual activity, general stress. Now, none of this matters. I just feel good.

I should add, I also include plenty of cultured foods in my diet, such as delicious homemade kefir, yogurt, raw sauerkraut, and probiotics in pill form. I am convinced this, too, helps prostatitis by improving the ecology of the colon. Considering the proximity of the colon to the bladder, and other male anatomy, it’s easy to see how a fungal overgrowth in the gut can lead to candida migrating into prostate tissues. Furthermore, it’s thought many of us are allergic to fungal pathogens, so once they invade tissues the immune system makes matters worse by mounting an ineffective inflammatory response.

Again, if hookworm tame the immune system, and a low-grade fungal infection is the trigger, it’s clear to me how helminthic therapy might play a role in easing prostatitis. I’ll have more to say about the impact of adding probiotic foods to my diet, and its effect on general inflammation, in a future post.

I’d appreciate hearing from you all in the comments section — of those doing helminthic therapy, is it helping to curb autoimmune response? And how many of you men out there have noticed if it helps with prostatitis? We self-experimenters are learning a lot about controlling inflammation, so much so that my doctors are really interested in updates — much of it gathered from you. Hopefully in time our knowledge can have an impact on mainstream medicine. Meanwhile, let’s keep up the good work!

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More Whipworm for Ulcerative Colitis Flare

My gut has been doing incredibly well ever since starting helminthic therapy back in late April, 2011. On August 8th I had to take Levaquin antibiotics for 7 days, and this “stunned” my worms enough that they no longer were providing anti-inflammatory benefits. Three days ago I noticed the first hint of an ulcerative colitis flare: a little mucous, some heat in my left abdomen around the descending colon. Sure enough, a day later I had a slight bit of blood on the TP. Those who suffer from UC know all about this. It’s when you start trying to decide how best to get rid of the inflammation.Watch Full Movie Online Streaming Online and Download

In my case, I’ve had good luck with dietary changes, but only for maintenance. The “big gun” of a decadron IV in the hospital works, as does Imuran, but each of these meds have horrid side effects. And with “dysautonomia” now affecting me, who knows how I would react, even if taking a small dose of prednisone.

So I started thinking about that 1500 whipworm top off dose in my fridge. Trichiura Trichuris to my rescue? I downed all 1500 in one gulp. If my immune system needs a “suitable target” for a distraction, I’ve certainly given it that. Speaking of, over the last 10 years, the luckiest I ever got was catching a cold of some sort while I was flaring. It was enough to take the immune attack off my gut, and focus it on the “bug” instead. Here it is almost week 20 after my first inoculation, and I’m aiming for a similar response with this 2nd dose of helminthic therapy.

In an ideal world I would have had a spare vial of Necator Americanus hookworm, and inoculated with those instead. I think my body tends to get along with them a bit better than the TT whipworm, but I have no solid proof of that, only a hunch. Anyway, so it goes — we work with what we’ve got. Now I’m pondering the coming wave of side effects. Since my body already knows these critters, having taken 500 of them in late April, I don’t anticipate the same intense reaction, but time will tell.

I’m hoping this latest batch of “old friends” keeps me healthy until the initial round (55 hookworm and 500 whipworm) perk up from the antibiotics. It usually takes about 6 to 8 weeks, so they should all be “online” and laying their eggs again by October 15th. Meanwhile, goooo, worms. 🙂

Healing from POTS

How did I get here? My symptoms of a stuffy nose and breathing trouble began after a motorcycle accident 22 years ago. At the time, I was more concerned about the rest of my body than my neck. It was stiff and sore for a few weeks, but I shook it off, and moved forward in life. About a month after the accident I began getting asthma attacks that would start with a stuffy nose. Tachycardia was also an issue, cropping up when I was exposed to allergens like house dust. Too bad some doctor back then didn’t order imaging studies of my neck. They probably would have seen the loss of normal curvature (lordosis) of my cervical spine, a condition known as “kyphosis”, which can be caused by traumatic injury.

I saw a neurosurgeon last week, and he felt surgery to open up my cervical spinal channel would improve my symptoms. He couldn’t promise anything — a favorable outcome, reduction or elimination of any specific symptoms, and he cautioned I might come out of the surgery feeling worse. “I can’t predict the future”, he said more than once. He suggested gentle, focused chiropractic, and neck traction, as things to try instead of surgery. Overall, his was an honest assessment, and one I could appreciate. But I’m not ready for someone to cut into my neck yet. And this particular surgeon seemed to know nothing about POTS. I described my symptoms and he referred to them as “vague” or “diffused”. To anyone familiar with dysautonomia, I would consider my description as classic, and typical, of autonomic nerve dysfunction, orthostatic intolerance, but these are not common diagnoses, unfortunately.

So I’m trying to tackle my health issues on a limited budget, and get the most impact I can for the effort. Neurofeedback worked well to deal with the background anxiety of illness. All these symptoms take their toll, and I felt these sessions were soothing me, but the effects only lasted a few days, and they were not cheap.

In the last week I’ve seen a new chiropractor who uses the “activator” method. It’s a precision hand tool that delivers a measured, consistent pulse of pressure to the spine, in a focused, gentle way. Most of the time you barely feel the adjustment, but it does work. I’ve noticed the effect bloom over the course of three or 4 days after. And this chiropractor is working in a very methodical way, starting from my hips and low back, paying attention to leg length, and then testing 嘉盛外汇 various neurological responses to find subluxations all the way up to my cervical spine. After 3 visits I can say i’m feeling a noticeable improvement, and I plan to continue treatment as long as I can. Thinking back over the development of my health issues, chiropractic has been one of the most helpful, but also has been damaging, when the wrong approach was applied at the wrong time. I want to stick with rehabilitating my cervical spine as much as possible, since it seems to be the source of so many issues.

POTS, be it hyperadrenergic like I seem to have (diagnosis pending), or the more conventional hypotension form, can also have an autoimmune component. The last few blood pressure spikes I’ve had didn’t seem overly related to head position, neck movement, etc. Sometimes my neck and head just starts to get hot, and I can feel my pulse and BP rising, usually after exercise or eating a meal. Both activities can release histamines, which in turn can activate mast cells. MCAD, or mast cell activation disorder, is a theoretical cause of POTS according to . They’ve found for certain patients an antihistamine will control symptoms just as well as more conventional approaches like beta blockers or blood pressure medications.

Diet is something I’ve been tinkering with for about a decade, and it has consistently yielded good results. Not necessarily linear progress, but the overall trend has been favorable. Two days ago I decided to give up dairy products altogether, and this was after a dairy holiday of two days reduced or eliminated many of my symptoms. Things like tinnitus — now nearly gone after a weekend of being dairy free. The fullness in my ears, congestion in my sinuses and nasal passages, slowly getting better now. My overall mood seems more stable, less anxious, less brain fog and fatigue. This has a very interesting theory about casein allergy and how improperly digested casein can affect neurotransmitters, even months after stopping dairy consumption. Basically, they are suggesting casein peptides can “lock up” certain receptors in the brain and create a wide range of neurological symptoms, including insomnia.

Sleep, for me, is the final frontier. Just as I thought I was sorting it out, last night I had another episode where I went past the 11pm tipping point, and was soon staring at a clock reading 1:45AM, with pulse pounding. In moments like this, I’ve decided to just take half a Klonopin, which for me is half the lowest .5MG dose, and go to sleep. It works. And sleep is too precious to miss, especially since going without for a night makes the POTS symptoms much worse.

The ultimate goal, of course, is to sleep well without any pharmaceutical aid whatsoever. I’m hoping with diet, chiropractic, and things like consistent exercise and meditation, I can achieve this in the near future.

I always seem to wrap up with a thought about the worms. My helminthic therapy has been paused by the use of Levaquin antibiotic, but the hookworm and whipworm should be back “online”, laying their eggs, in another 6 to 7 weeks (October 15th). I’m hoping by that time I’ll start to experience their longer term benefits, which could include a reduction of most, if not all, allergic symptoms. Can these worms “cure” my POTS? Well, , all my various aches and pains disappeared. I’d settle for feeling a fraction of that relief now, and have high hopes helminthic therapy will compliment all the other measures I’m taking.

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